Nuclear Factor of Activated T Cells c Is a Target of p38 Mitogen-Activated Protein Kinase in T Cells

p38 mitogen activated protein kinase (MAPK) is essential for T-cell activation. Here we demonstrated that nuclear factor of activated T cells (NFAT) is a direct target of p38 MAPK. Inhibition of p38 MAPK led to selective inactivation of NFAT in T cells. We further linked a strict requirement of p38...

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Bibliografiset tiedot
Päätekijät: Wu, Chia-Cheng, Hsu, Shu-Ching, Shih, Hsiu-ming, Lai, Ming-Zong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Cell Growth and Development
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC193716/
https://ncbi.nlm.nih.gov/pubmed/12944472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6442-6454.2003
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