GATA- and Smad1-Dependent Enhancers in the Smad7 Gene Differentially Interpret Bone Morphogenetic Protein Concentrations

Smad7, an inhibitor of transforming growth factor beta superfamily signaling, is induced by bone morphogenetic protein (BMP) in an inhibitory feedback loop. Here, we identify multiple BMP response elements (BREs) in the Smad7 gene and demonstrate that they function differentially to interpret BMP si...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Benchabane, Hassina, Wrana, Jeffrey L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12944489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.18.6646-6661.2003
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