Highly Restricted Localization of RNA Polymerase II within a Locus Control Region of a Tissue-Specific Chromatin Domain

RNA polymerase II (Pol II) can associate with regulatory elements far from promoters. For the murine β-globin locus, Pol II binds the β-globin locus control region (LCR) far upstream of the β-globin promoters, independent of recruitment to and activation of the βmajor promoter. We describe here an a...

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Detalhes bibliográficos
Main Authors: Johnson, Kirby D., Grass, Jeffrey A., Park, Changwon, Im, Hogune, Choi, Kyunghee, Bresnick, Emery H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193707/
https://ncbi.nlm.nih.gov/pubmed/12944475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6484-6493.2003
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