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Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis

BACKGROUND: Myelin Oligodendrocyte Glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) is the most commonly used mouse model for multiple sclerosis (MS). During the of progression of EAE, microglia, the immunocompetent cells of the brain, become activated and accumulate around...

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Bibliografski detalji
Glavni autori: Bhasin, Madhuri, Wu, Muzhou, Tsirka, Stella E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937009/
https://ncbi.nlm.nih.gov/pubmed/17634104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-8-10
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