A crucial role for thiol antioxidants in estrogen-deficiency bone loss

The mechanisms through which estrogen prevents bone loss are uncertain. Elsewhere, estrogen exerts beneficial actions by suppression of reactive oxygen species (ROS). ROS stimulate osteoclasts, the cells that resorb bone. Thus, estrogen might prevent bone loss by enhancing oxidant defenses in bone....

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Autors principals: Lean, Jenny M., Davies, Julie T., Fuller, Karen, Jagger, Christopher J., Kirstein, Barrie, Partington, Geoffrey A., Urry, Zoë L., Chambers, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC193670/
https://ncbi.nlm.nih.gov/pubmed/12975476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318859
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