Comparing protein abundance and mRNA expression levels on a genomic scale

Attempts to correlate protein abundance with mRNA expression levels have had variable success. We review the results of these comparisons, focusing on yeast. In the process, we survey experimental techniques for determining protein abundance, principally two-dimensional gel electrophoresis and mass-...

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Bibliographic Details

Published in:	Genome Biol
Main Authors:	Greenbaum, Dov, Colangelo, Christopher, Williams, Kenneth, Gerstein, Mark
Format:	Artigo
Language:	Inglês
Published:	BMC 2003
Subjects:	Opinion
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2003-4-9-117
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