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Comparing protein abundance and mRNA expression levels on a genomic scale

Attempts to correlate protein abundance with mRNA expression levels have had variable success. We review the results of these comparisons, focusing on yeast. In the process, we survey experimental techniques for determining protein abundance, principally two-dimensional gel electrophoresis and mass-...

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Detalhes bibliográficos
Main Authors: Greenbaum, Dov, Colangelo, Christopher, Williams, Kenneth, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193646/
https://ncbi.nlm.nih.gov/pubmed/12952525
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