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An ultrasensitive Ca(2+)/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling

The strength of hippocampal synapses can be persistently increased by signals that activate Ca(2+)/calmodulin-dependent protein kinase II (CaMKII). This CaMKII-dependent long-term potentiation is important for hippocampal learning and memory. In this work we show that CaMKII exhibits an intriguing s...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bradshaw, J. Michael, Kubota, Yoshi, Meyer, Tobias, Schulman, Howard
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12928489/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1932759100
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