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DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus
A plasmid DNA directing transcription of the infectious full-length RNA genome of Kunjin (KUN) virus in vivo from a mammalian expression promoter was used to vaccinate mice intramuscularly. The KUN viral cDNA encoded in the plasmid contained the mutation in the NS1 protein (Pro-250 to Leu) previousl...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193583/ https://ncbi.nlm.nih.gov/pubmed/12917491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834270100 |
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