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Estimating the distribution of fitness effects from DNA sequence data: Implications for the molecular clock
We present a method for estimating the distribution of fitness effects of new amino acid mutations when those mutations can be assumed to be slightly advantageous, slightly deleterious, or strongly deleterious. We apply the method to mitochondrial data from several different species. In the majority...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193562/ https://ncbi.nlm.nih.gov/pubmed/12925735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1833064100 |
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