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Estimating the distribution of fitness effects from DNA sequence data: Implications for the molecular clock

We present a method for estimating the distribution of fitness effects of new amino acid mutations when those mutations can be assumed to be slightly advantageous, slightly deleterious, or strongly deleterious. We apply the method to mitochondrial data from several different species. In the majority...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Piganeau, Gwenaël, Eyre-Walker, Adam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC193562/
https://ncbi.nlm.nih.gov/pubmed/12925735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1833064100
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