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Hypoxia-Inducible Factor-1 Facilitates Cervical Cancer Progression in Human Papillomavirus Type 16 Transgenic Mice

Advanced cervical cancer remains a vexing clinical challenge despite screening programs. Many of these cancers are hypoxic, and expression of the α subunit of the major regulator of the hypoxic cellular response, the transcription factor hypoxia-inducible factor-1 (HIF-1), is correlated with poor pr...

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Main Authors: Lu, Zhi Hong, Wright, Jason D., Belt, Brian, Cardiff, Robert D., Arbeit, Jeffrey M.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934541/
https://ncbi.nlm.nih.gov/pubmed/17600126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061138
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