A Protein Toxin from the Sea Anemone Phyllodiscus semoni Targets the Kidney and Causes a Severe Renal Injury with Predominant Glomerular Endothelial Damage

Envenomation by the sea anemone Phyllodiscus semoni causes fulminant dermatitis and, rarely, acute renal failure in humans. Here, we investigated whether the venom extracted from the nematocysts (PsTX-T) was nephrotoxic when administered intravenously in rats and whether PsTX-T induced activation of...

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Main Authors: Mizuno, Masashi, Nozaki, Masatoshi, Morine, Nobuya, Suzuki, Norihiko, Nishikawa, Kazuhiro, Morgan, B. Paul, Matsuo, Seiichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2007
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934535/
https://ncbi.nlm.nih.gov/pubmed/17600120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060984
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