A Protein Toxin from the Sea Anemone Phyllodiscus semoni Targets the Kidney and Causes a Severe Renal Injury with Predominant Glomerular Endothelial Damage

Envenomation by the sea anemone Phyllodiscus semoni causes fulminant dermatitis and, rarely, acute renal failure in humans. Here, we investigated whether the venom extracted from the nematocysts (PsTX-T) was nephrotoxic when administered intravenously in rats and whether PsTX-T induced activation of...

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Hlavní autoři: Mizuno, Masashi, Nozaki, Masatoshi, Morine, Nobuya, Suzuki, Norihiko, Nishikawa, Kazuhiro, Morgan, B. Paul, Matsuo, Seiichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2007
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934535/
https://ncbi.nlm.nih.gov/pubmed/17600120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060984
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