Synaptopodin Protects Against Proteinuria by Disrupting Cdc42:IRSp53:Mena Signaling Complexes in Kidney Podocytes

The actin-based foot processes of kidney podocytes and the interposed slit diaphragm form the final barrier to proteinuria. Mutations affecting several podocyte proteins cause disruption of the filtration barrier and rearrangement of the highly dynamic podocyte actin cytoskeleton. Proteins regulatin...

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Bibliografiska uppgifter
Huvudupphovsmän: Yanagida-Asanuma, Etsuko, Asanuma, Katsuhiko, Kim, Kwanghee, Donnelly, Mary, Young Choi, Hoon, Hyung Chang, Jae, Suetsugu, Shiro, Tomino, Yasuhiko, Takenawa, Tadaomi, Faul, Christian, Mundel, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2007
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934530/
https://ncbi.nlm.nih.gov/pubmed/17569780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070075
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