Synaptopodin Protects Against Proteinuria by Disrupting Cdc42:IRSp53:Mena Signaling Complexes in Kidney Podocytes

The actin-based foot processes of kidney podocytes and the interposed slit diaphragm form the final barrier to proteinuria. Mutations affecting several podocyte proteins cause disruption of the filtration barrier and rearrangement of the highly dynamic podocyte actin cytoskeleton. Proteins regulatin...

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Detalhes bibliográficos
Main Authors: Yanagida-Asanuma, Etsuko, Asanuma, Katsuhiko, Kim, Kwanghee, Donnelly, Mary, Young Choi, Hoon, Hyung Chang, Jae, Suetsugu, Shiro, Tomino, Yasuhiko, Takenawa, Tadaomi, Faul, Christian, Mundel, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934530/
https://ncbi.nlm.nih.gov/pubmed/17569780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070075
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