A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
Adenoviruses are attractive vectors for the delivery of foreign genes into mammalian cells for gene therapy. However, current vectors retain many viral genes that, when expressed at low levels, contribute to the induction of a host immune response against transduced cells. We have developed a helper...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8942974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13565 |
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