Structure–function studies of the G-domain from human gem, a novel small G-protein

Gem, a member of the Rad, Gem/Kir subfamily of small G-proteins, has unique sequence features. We report here the crystallographic structure determination of the Gem G-domain in complex with nucleotide to 2.4 Å resolution. Although the basic Ras protein fold is maintained, the Gem switch regions emp...

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Bibliografiska uppgifter
Huvudupphovsmän: Opatowsky, Yarden, Sasson, Yehezkel, Shaked, Isabella, Ward, Yvona, Chomsky-Hecht, Orna, Litvak, Yael, Selinger, Zvi, Kelly, Kathleen, Hirsch, Joel A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934412/
https://ncbi.nlm.nih.gov/pubmed/17052716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.09.067
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