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Aeromonas salmonicida Toxin AexT Has a Rho Family GTPase-Activating Protein Domain

The N terminus of the Aeromonas salmonicida ADP-ribosylating toxin AexT displays in vitro GTPase-activating protein (GAP) activity for Rac1, CDC42, and RhoA. HeLa cells transfected with the AexT N terminus exhibit rounding and actin disordering. We propose that the Aeromonas salmonicida AexT toxin i...

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Bibliografiske detaljer
Main Authors: Litvak, Yael, Selinger, Zvi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899366/
https://ncbi.nlm.nih.gov/pubmed/17237181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01358-06
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