Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

Cubitus interruptus (Ci) is a transcriptional factor that is positively regulated by the hedgehog (hh) signaling pathway. Recent work has shown that a 75-kDa proteolytic product of the full-length CI protein translocates to the nucleus and represses the transcription of CI target genes. In cells tha...

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Bibliographic Details
Main Authors: Chen, Yang, Gallaher, Nicole, Goodman, Richard H., Smolik, Sarah M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19341/
https://ncbi.nlm.nih.gov/pubmed/9482888
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