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Directed Molecular Screening for RecA ATPase Inhibitors
The roles of bacterial RecA in the evolution and transmission of antibiotic resistance genes make it an attractive target for inhibition by small molecules. We report two complementary fluorescence-based ATPase assays that were used to screen for inhibitors of RecA. We elected to employ the ADP-link...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933586/ https://ncbi.nlm.nih.gov/pubmed/17499507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.04.013 |
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