Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labelled ganglioside GM1

Ganglioside GM1 and its seven potential catabolic products: asialo-GM1, GM2, asialo-GM2, GM3, Lac-Cer, Glc-Cer and Cer, were labelled with tetramethylrhodamine (TMR) to permit ultra-sensitive analysis using laser-induced fluorescence (LIF) detection. The preparation involved acylation of the homogen...

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Bibliographic Details
Main Authors: Larsson, E. Andreas, Olsson, Ulf, Whitmore, Colin, Martins, Rita, Tettamanti, Guido, Schnaar, Ronald L., Dovichi, Norman J., Palcic, Monica M., Hindsgaul, Ole
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933503/
https://ncbi.nlm.nih.gov/pubmed/17069778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2006.10.002
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