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Nine Orders of Magnitude Dynamic Range: Picomolar to Millimolar Concentration Measurement in Capillary Electrophoresis with Laser Induced Fluorescence Detection Employing Cascaded Avalanche Photodiode Photon Counters

The dynamic range of capillary electrophoresis analysis is ultimately limited by molecular shot noise at low concentrations and by concentration-induced band broadening at high concentrations. We report a system that approaches these fundamental limits. A laser-induced fluorescence detector is repor...

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Detalhes bibliográficos
Main Authors: Dada, Oluwatosin O., Essaka, David C., Hindsgaul, Ole, Palcic, Monica M., Prendergast, Jillian, Schnaar, Ronald L., Dovichi, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072807/
https://ncbi.nlm.nih.gov/pubmed/21410138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac103374x
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