PET Imaging of CRF1 with [(11)C]R121920 and [(11)C]DMP696: Is the Target of Sufficient Density?

AIM: Overstimulation of the CRF type 1 receptor (CRF1) is implicated in anxiety and depressive disorders. The aim of this study was to investigate the in vivo binding characteristics of [(11)C]R121920 and [(11)C]DMP696 in the non‐human primate for application in positron emission tomography (PET) st...

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Main Authors: Sullivan, Gregory M., Parsey, Ramin V., Kumar, J. S. Dileep, Arango, Victoria, Kassir, Suham A., Huang, Yung‐yu, Simpson, Norman R., Van Heertum, Ronald L., Mann, J. John
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933490/
https://ncbi.nlm.nih.gov/pubmed/17499724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.01.012
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