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Molecular Basis of Resistance to Muramidase and Cationic Antimicrobial Peptide Activity of Lysozyme in Staphylococci

It has been shown recently that modification of peptidoglycan by O-acetylation renders pathogenic staphylococci resistant to the muramidase activity of lysozyme. Here, we show that a Staphylococcus aureus double mutant defective in O-acetyltransferase A (OatA), and the glycopeptide resistance-associ...

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Detalhes bibliográficos
Main Authors: Herbert, Silvia, Bera, Agnieszka, Nerz, Christiane, Kraus, Dirk, Peschel, Andreas, Goerke, Christiane, Meehl, Michael, Cheung, Ambrose, Götz, Friedrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933452/
https://ncbi.nlm.nih.gov/pubmed/17676995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030102
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