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Functional dynamics of H3K9 methylation during meiotic prophase progression

Histone H3 lysine 9 (H3K9) methylation is a crucial epigenetic mark of heterochromatin formation and transcriptional silencing. G9a is a major mammalian H3K9 methyltransferase at euchromatin and is essential for mouse embryogenesis. Here we describe the roles of G9a in germ cell development. Mutant...

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Detalhes bibliográficos
Main Authors: Tachibana, Makoto, Nozaki, Masami, Takeda, Naoki, Shinkai, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933398/
https://ncbi.nlm.nih.gov/pubmed/17599069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601767
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