Induction of MxA Gene Expression by Influenza A Virus Requires Type I or Type III Interferon Signaling

The human MxA gene belongs to the class of interferon (IFN)-stimulated genes (ISGs) involved in antiviral resistance against influenza viruses. Here, we studied the requirements for MxA induction by influenza A virus infection. MxA is transcriptionally upregulated by type I (alpha and beta) and type...

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Main Authors: Holzinger, Dirk, Jorns, Carl, Stertz, Silke, Boisson-Dupuis, Stéphanie, Thimme, Robert, Weidmann, Manfred, Casanova, Jean-Laurent, Haller, Otto, Kochs, Georg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Cellular Response to Infection
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933351/
https://ncbi.nlm.nih.gov/pubmed/17494065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00546-06
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