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Protracted Course of Lymphocytic Choriomeningitis Virus WE Infection in Early Life: Induction but Limited Expansion of CD8(+) Effector T Cells and Absence of Memory CD8(+) T Cells

Viral infections in human infants frequently follow a protracted course, with higher viral loads and delayed viral clearance compared to viral infections in older children. To identify the mechanisms responsible for this protracted pattern of infection, we developed an infant infection murine model...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Belnoue, Elodie, Fontannaz-Bozzotti, Paola, Grillet, Stéphane, Lambert, Paul-Henri, Siegrist, Claire-Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933347/
https://ncbi.nlm.nih.gov/pubmed/17494081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00062-07
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