Dendritic Cells Infected with vpr-Positive Human Immunodeficiency Virus Type 1 Induce CD8(+) T-Cell Apoptosis via Upregulation of Tumor Necrosis Factor Alpha

Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) plays a crucial role in viral replication and pathogenesis by inducing cell cycle arrest, apoptosis, translocation of preintegration complex, potentiation of glucocorticoid action, impairment of dendritic cell (DC) maturation, and T-c...

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Bibliografiska uppgifter
Huvudupphovsmän: Majumder, Biswanath, Venkatachari, Narasimhan J., Schafer, Elizabeth A., Janket, Michelle L., Ayyavoo, Velpandi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933341/
https://ncbi.nlm.nih.gov/pubmed/17475642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00893-06
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