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Dendritic Cells Infected with vpr-Positive Human Immunodeficiency Virus Type 1 Induce CD8(+) T-Cell Apoptosis via Upregulation of Tumor Necrosis Factor Alpha
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) plays a crucial role in viral replication and pathogenesis by inducing cell cycle arrest, apoptosis, translocation of preintegration complex, potentiation of glucocorticoid action, impairment of dendritic cell (DC) maturation, and T-c...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933341/ https://ncbi.nlm.nih.gov/pubmed/17475642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00893-06 |
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