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The X Protein of Borna Disease Virus Serves Essential Functions in the Viral Multiplication Cycle

The X gene of Borna disease virus (BDV) encodes a nonstructural 10-kDa protein that can interact with viral polymerase cofactor P, thus regulating polymerase activity. It remained unknown whether X is essential for virus multiplication. All our attempts to generate mutant BDV with a nonfunctional X...

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Detalhes bibliográficos
Main Authors: Poenisch, Marion, Wille, Sandra, Ackermann, Andreas, Staeheli, Peter, Schneider, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933315/
https://ncbi.nlm.nih.gov/pubmed/17428855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02468-06
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