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Adaptation of Borna Disease Virus to New Host Species Attributed to Altered Regulation of Viral Polymerase Activity

Borna disease virus (BDV) can persistently infect the central nervous system of a broad range of mammalian species. Mice are resistant to infections with primary BDV isolates, but certain laboratory strains can be adapted to replicate in mice. We determined the molecular basis of adaptation by study...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ackermann, Andreas, Staeheli, Peter, Schneider, Urs
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951315/
https://ncbi.nlm.nih.gov/pubmed/17522214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00334-07
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