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Cytokine-Independent Upregulation of MDA5 in Viral Infection
The RNA helicases RIG-I and MDA5 detect virus infection of dendritic cells (DCs) leading to cytokine induction. Maximal sensitivity for virus detection by these helicases is obtained after their upregulation, which is thought to occur primarily through type I interferon (IFN) signaling. Here we demo...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933291/ https://ncbi.nlm.nih.gov/pubmed/17475649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00545-07 |
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