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Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

Viral encephalitis is a major cause of morbidity and mortality worldwide, yet there is no proven efficacious therapy for most viral infections of the central nervous system (CNS). Many of the viruses that cause encephalitis induce apoptosis and activate c-Jun N-terminal kinase (JNK) following infect...

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Detalhes bibliográficos
Main Authors: Beckham, J. David, Goody, Robin J., Clarke, Penny, Bonny, Christophe, Tyler, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933289/
https://ncbi.nlm.nih.gov/pubmed/17475657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00467-07
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