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Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

Viral encephalitis is a major cause of morbidity and mortality worldwide, yet there is no proven efficacious therapy for most viral infections of the central nervous system (CNS). Many of the viruses that cause encephalitis induce apoptosis and activate c-Jun N-terminal kinase (JNK) following infect...

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Détails bibliographiques
Auteurs principaux: Beckham, J. David, Goody, Robin J., Clarke, Penny, Bonny, Christophe, Tyler, Kenneth L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933289/
https://ncbi.nlm.nih.gov/pubmed/17475657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00467-07
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