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Use of a Genetically Defined Double Mutant Strain of Bordetella bronchiseptica Lacking Adenylate Cyclase and Type III Secretion as a Live Vaccine

While most vaccines consisting of killed bacteria induce high serum antibody titers, they do not always confer protection as effective as that induced by infection, particularly against mucosal pathogens. Bordetella bronchiseptica is a gram-negative respiratory pathogen that is endemic in many nonhu...

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Main Authors: Mann, Paul, Goebel, Elizabeth, Barbarich, James, Pilione, Mylisa, Kennett, Mary, Harvill, Eric
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932943/
https://ncbi.nlm.nih.gov/pubmed/17452472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01648-06
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