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Use of a Genetically Defined Double Mutant Strain of Bordetella bronchiseptica Lacking Adenylate Cyclase and Type III Secretion as a Live Vaccine

While most vaccines consisting of killed bacteria induce high serum antibody titers, they do not always confer protection as effective as that induced by infection, particularly against mucosal pathogens. Bordetella bronchiseptica is a gram-negative respiratory pathogen that is endemic in many nonhu...

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Detalhes bibliográficos
Main Authors: Mann, Paul, Goebel, Elizabeth, Barbarich, James, Pilione, Mylisa, Kennett, Mary, Harvill, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932943/
https://ncbi.nlm.nih.gov/pubmed/17452472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01648-06
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