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Heterogeneity in the Activity of Mexican Helicobacter pylori Strains in Gastric Epithelial Cells and Its Association with Diversity in the cagA Gene

Helicobacter pylori CagA is translocated into gastric epithelial cells by a type IV secretion system and interacts with the Src homology 2 phosphatase, altering cell morphology. Multiple EPIYA motifs in CagA are associated with increased activity in cells and with gastric cancer. The aim of this wor...

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Detalhes bibliográficos
Main Authors: Reyes-Leon, Adriana, Atherton, John C., Argent, Richard H., Puente, J. L., Torres, J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932923/
https://ncbi.nlm.nih.gov/pubmed/17438024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01951-06
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