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Cholesterol Depletion Reduces Helicobacter pylori CagA Translocation and CagA-Induced Responses in AGS Cells

Infection with Helicobacter pylori cagA-positive strains is associated with gastritis, ulcerations, and gastric cancer. CagA is translocated into infected epithelial cells by a type IV secretion system and can be tyrosine phosphorylated, inducing signal transduction and motogenic responses in epithe...

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Detalhes bibliográficos
Main Authors: Lai, Chih-Ho, Chang, Yun-Chieh, Du, Shin-Yi, Wang, Hung-Jung, Kuo, Chun-Hsien, Fang, Shih-Hua, Fu, Hua-Wen, Lin, Hui-Hao, Chiang, Ann-Shyn, Wang, Wen-Ching
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446742/
https://ncbi.nlm.nih.gov/pubmed/18443091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00365-08
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