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Relaxed Cleavage Specificity of an Immunoglobulin A1 Protease from Neisseria meningitidis

Respiratory pathogens, such as Neisseria meningitidis, secrete site-specific proteases able to cleave human immunoglobulin A1 (IgA1), the first line of defense at mucosal membranes. Bacterial isolates show wide variability in IgA1 protease activity, and those isolated from patients with clinical inf...

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Autors principals: Vitovski, Srdjan, Sayers, Jon R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932897/
https://ncbi.nlm.nih.gov/pubmed/17353288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01671-06
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