Complement Receptor 3 and Toll-Like Receptor 4 Act Sequentially in Uptake and Intracellular Killing of Unopsonized Salmonella enterica Serovar Typhimurium by Human Neutrophils

The uptake and subsequent killing of Salmonella enterica serovar Typhimurium by human neutrophils was studied. In particular, two pattern recognition receptors, complement receptor 3 (CR3) and Toll-like receptor 4 (TLR4), were found to be essential for the efficient uptake and activation, respective...

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Main Authors: van Bruggen, Robin, Zweers, Debby, van Diepen, Angela, van Dissel, Jaap T., Roos, Dirk, Verhoeven, Arthur J., Kuijpers, Taco W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932891/
https://ncbi.nlm.nih.gov/pubmed/17353285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01111-06
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