A Superoxide-Hypersusceptible Salmonella enterica Serovar Typhimurium Mutant Is Attenuated but Regains Virulence in p47(phox−/−) Mice

Salmonella enterica serovar Typhimurium is a gram-negative, facultative intracellular pathogen that predominantly invades mononuclear phagocytes and is able to establish persistent infections. One of the innate defense mechanisms of phagocytic cells is the production of reactive oxygen species, incl...

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Detalhes bibliográficos
Main Authors: van Diepen, Angela, van der Straaten, Tahar, Holland, Steven M., Janssen, Riny, van Dissel, Jaap T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127934/
https://ncbi.nlm.nih.gov/pubmed/11953403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2614-2621.2002
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