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A Superoxide-Hypersusceptible Salmonella enterica Serovar Typhimurium Mutant Is Attenuated but Regains Virulence in p47(phox−/−) Mice

Salmonella enterica serovar Typhimurium is a gram-negative, facultative intracellular pathogen that predominantly invades mononuclear phagocytes and is able to establish persistent infections. One of the innate defense mechanisms of phagocytic cells is the production of reactive oxygen species, incl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Diepen, Angela, van der Straaten, Tahar, Holland, Steven M., Janssen, Riny, van Dissel, Jaap T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127934/
https://ncbi.nlm.nih.gov/pubmed/11953403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2614-2621.2002
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