A Superoxide-Hypersusceptible Salmonella enterica Serovar Typhimurium Mutant Is Attenuated but Regains Virulence in p47(phox−/−) Mice

Salmonella enterica serovar Typhimurium is a gram-negative, facultative intracellular pathogen that predominantly invades mononuclear phagocytes and is able to establish persistent infections. One of the innate defense mechanisms of phagocytic cells is the production of reactive oxygen species, incl...

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Bibliographic Details
Main Authors: van Diepen, Angela, van der Straaten, Tahar, Holland, Steven M., Janssen, Riny, van Dissel, Jaap T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127934/
https://ncbi.nlm.nih.gov/pubmed/11953403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2614-2621.2002
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