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Chloramphenicol Is a Substrate for a Novel Nitroreductase Pathway in Haemophilus influenzae

The p-nitroaromatic antibiotic chloramphenicol has been used extensively to treat life-threatening infections due to Haemophilus influenzae and Neisseria meningitidis; its mechanism of action is the inhibition of protein synthesis. We found that during incubation with H. influenzae cells and lysates...

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Detalhes bibliográficos
Main Authors: Smith, Arnold L., Erwin, Alice L., Kline, Toni, Unrath, William C. T., Nelson, Kevin, Weber, Allan, Howald, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932534/
https://ncbi.nlm.nih.gov/pubmed/17526758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00087-07
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