Bound To Shock: Protection from Lethal Endotoxemic Shock by a Novel, Nontoxic, Alkylpolyamine Lipopolysaccharide Sequestrant

Lipopolysaccharide (LPS), or endotoxin, a structural component of gram-negative bacterial outer membranes, plays a key role in the pathogenesis of septic shock, a syndrome of severe systemic inflammation which leads to multiple-system organ failure. Despite advances in antimicrobial chemotherapy, se...

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Bibliografiske detaljer
Main Authors: Sil, Diptesh, Shrestha, Anurupa, Kimbrell, Matthew R., Nguyen, Thuan B., Adisechan, Ashok K., Balakrishna, Rajalakshmi, Abbo, Benjamin G., Malladi, Subbalakshmi, Miller, Kelly A., Short, Shannon, Cromer, Jens R., Arora, Shravan, Datta, Apurba, David, Sunil A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932507/
https://ncbi.nlm.nih.gov/pubmed/17548488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00200-07
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