Bound To Shock: Protection from Lethal Endotoxemic Shock by a Novel, Nontoxic, Alkylpolyamine Lipopolysaccharide Sequestrant

Lipopolysaccharide (LPS), or endotoxin, a structural component of gram-negative bacterial outer membranes, plays a key role in the pathogenesis of septic shock, a syndrome of severe systemic inflammation which leads to multiple-system organ failure. Despite advances in antimicrobial chemotherapy, se...

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Bibliografski detalji
Glavni autori: Sil, Diptesh, Shrestha, Anurupa, Kimbrell, Matthew R., Nguyen, Thuan B., Adisechan, Ashok K., Balakrishna, Rajalakshmi, Abbo, Benjamin G., Malladi, Subbalakshmi, Miller, Kelly A., Short, Shannon, Cromer, Jens R., Arora, Shravan, Datta, Apurba, David, Sunil A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Experimental Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932507/
https://ncbi.nlm.nih.gov/pubmed/17548488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00200-07
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