Bound To Shock: Protection from Lethal Endotoxemic Shock by a Novel, Nontoxic, Alkylpolyamine Lipopolysaccharide Sequestrant

Lipopolysaccharide (LPS), or endotoxin, a structural component of gram-negative bacterial outer membranes, plays a key role in the pathogenesis of septic shock, a syndrome of severe systemic inflammation which leads to multiple-system organ failure. Despite advances in antimicrobial chemotherapy, se...

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Bibliografische gegevens
Hoofdauteurs: Sil, Diptesh, Shrestha, Anurupa, Kimbrell, Matthew R., Nguyen, Thuan B., Adisechan, Ashok K., Balakrishna, Rajalakshmi, Abbo, Benjamin G., Malladi, Subbalakshmi, Miller, Kelly A., Short, Shannon, Cromer, Jens R., Arora, Shravan, Datta, Apurba, David, Sunil A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932507/
https://ncbi.nlm.nih.gov/pubmed/17548488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00200-07
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