Bound To Shock: Protection from Lethal Endotoxemic Shock by a Novel, Nontoxic, Alkylpolyamine Lipopolysaccharide Sequestrant

Lipopolysaccharide (LPS), or endotoxin, a structural component of gram-negative bacterial outer membranes, plays a key role in the pathogenesis of septic shock, a syndrome of severe systemic inflammation which leads to multiple-system organ failure. Despite advances in antimicrobial chemotherapy, se...

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Detalhes bibliográficos
Main Authors: Sil, Diptesh, Shrestha, Anurupa, Kimbrell, Matthew R., Nguyen, Thuan B., Adisechan, Ashok K., Balakrishna, Rajalakshmi, Abbo, Benjamin G., Malladi, Subbalakshmi, Miller, Kelly A., Short, Shannon, Cromer, Jens R., Arora, Shravan, Datta, Apurba, David, Sunil A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932507/
https://ncbi.nlm.nih.gov/pubmed/17548488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00200-07
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