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Increasing the Efficiency of Variance Component Quantitative Trait Loci Analysis by Using Reduced-Rank Identity-by-Descent Matrices

Recent technological development in genetics has made large-scale marker genotyping fast and practicable, facilitating studies for detection of QTL in large general pedigrees. We developed a method that speeds up restricted maximum-likelihood (REML) algorithms for QTL analysis by simplifying the inv...

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Main Authors: Rönnegård, Lars, Mischenko, Kateryna, Holmgren, Sverker, Carlborg, Örjan
Formato: Artigo
Idioma:Inglês
Publicado: Copyright © 2007 by the Genetics Society of America 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931556/
https://ncbi.nlm.nih.gov/pubmed/17483421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.071977
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