Wordt geladen...

In Vitro Expansion of Erythroid Progenitors from Polycythemia Vera Patients Leads to Decrease in JAK2(V617F) Allele

OBJECTIVES: A G>T transversion in a tyrosine kinase JAK2 (V617F) was reported in over 80% of patients with polycythemia vera (PV). Current evidence suggests that JAK2(V617F) somatic mutation is involved in the pathogenesis of PV, since it confers erythropoietin independent proliferation to erythr...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Gaikwad, Amos, Nussenzveig, Roberto, Liu, Enli, Gottshalk, Stephen, Chang, KoTung, Prchal, Josef T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931508/
https://ncbi.nlm.nih.gov/pubmed/17379069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2006.12.007
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!