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Junction ribonuclease: An activity in Okazaki fragment processing

The initiator RNAs of mammalian Okazaki fragments are thought to be removed by RNase HI and the 5′-3′ flap endonuclease (FEN1). Earlier evidence indicated that the cleavage site of RNase HI is 5′ of the last ribonucleotide at the RNA-DNA junction on an Okazaki substrate. In current work, highly puri...

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Auteurs principaux: Murante, Richard S., Henricksen, Leigh A., Bambara, Robert A.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC19307/
https://ncbi.nlm.nih.gov/pubmed/9482870
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