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Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor

Induction of terminal differentiation represents a promising therapeutic approach to certain human malignancies. The peroxisome proliferator-activated receptor γ (PPARγ) and the retinoid X receptor α (RXRα) form a heterodimeric complex that functions as a central regulator of adipocyte differentiati...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tontonoz, Peter, Singer, Samuel, Forman, Barry M., Sarraf, Pasha, Fletcher, Jonathan A., Fletcher, Christopher D. M., Brun, Regina P., Mueller, Elisabetta, Altiok, Soner, Oppenheim, Heather, Evans, Ronald M., Spiegelman, Bruce M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.237
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