Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes

We have developed a new microarray-based genetic technique, named MGK (Monitoring of Gene Knockouts), for genome-wide identification of conditionally essential genes. MGK identified bacterial genes that are critical for fitness in the absence of aromatic amino acids, and was further applied to ident...

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Autores principales: Smith, Lisa K, Gomez, Maria J, Shatalin, Konstantin Y, Lee, Hyunwoo, Neyfakh, Alexander A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929150/
https://ncbi.nlm.nih.gov/pubmed/17519022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-5-r87
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