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Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis

BACKGROUND: Activated drotrecogin alfa (human activated protein C, rhAPC), is produced by recombinant DNA technology, and purports to improve clinical outcomes by counteracting the inflammatory and thrombotic consequences of severe sepsis. Controversy exists around the clinical benefits of this drug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costa, Vania, Brophy, James M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929064/
https://ncbi.nlm.nih.gov/pubmed/17592639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2253-7-5
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