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Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis

BACKGROUND: Activated drotrecogin alfa (human activated protein C, rhAPC), is produced by recombinant DNA technology, and purports to improve clinical outcomes by counteracting the inflammatory and thrombotic consequences of severe sepsis. Controversy exists around the clinical benefits of this drug...

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Detalhes bibliográficos
Main Authors: Costa, Vania, Brophy, James M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929064/
https://ncbi.nlm.nih.gov/pubmed/17592639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2253-7-5
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